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Dear Friend,
Thank you for your support of ADARC's mission to find solutions to the HIV/AIDS epidemic through scientific research. We want to share some of the scientific progress taking place in our laboratories, and hope you will enjoy being a part of future breakthroughs.

Dr. David Ho wins NIDA's 2011 Avant-Garde Award

 

David D. Ho, MD

David D. Ho, MD

 Dr. David Ho is the 2011 winner of the Avant-Garde Award, announced the National Institute on Drug Abuse. Dr. Ho plans to develop a new form of long-acting HIV therapy that has the potential to become the next generation of medications to treat HIV/AIDS. Currently, people infected with HIV-1 need to take medications daily in order to keep the virus at bay. Patients who are not able to follow treatment guidelines are not likely to remain healthy.

 

Dr. Ho's team is working to develop antibody-like molecules that can be administered monthly, which would help improve adherence to treatment in a safe and effective way. "These antibodies are well tolerated and have an excellent safety record, and can be administered infrequently because of their long half-life as compared to the small molecules in current therapies," said Dr. Ho.

 

The Avant-Garde award is granted each year by NIDA, part of the National Institutes of Health. The five-year, $2.5 million grant is designed to support individual scientists of exceptional creativity who propose cutting-edge and transformative approaches to major challenges in biomedical and behavioral research on drug abuse and HIV/AIDS. Selected scientists must show research projects of high-risk, but with potential for high impact. Dr. Ho is the only grantee this year.

 

 

 

You can support Dr. Ho's work.  

 

 

Meet our Interns

Each year, ADARC welcomes a number of interns who spend the summer months working in our laboratories and learning from our scientists. These young scientists are selected by ADARC's faculty due to their talent, scientific interests, and early career choices. From recent college graduates, to college students with their eyes on medical school, to extraordinary high school students, they all share a love for science that blossomed early, and an enthusiasm to contribute to end of the HIV/AIDS epidemic.

Sarah

Sarah Rapoport

  

Sarah Rapoport, an intern in Dr. David Ho's laboratory, started experimenting with science and medicine using her family as willing subjects. At nine years old, she inherited her father's old ophthalmoscope and doggedly made the rounds to relatives and friends around her family's Thanksgiving dinner table, asking, "Can I look in your ears? Later, she and her brother converted a blender into a centrifuge to remove the pulp from orange juice.  

 

Since then, her experiments have become more sophisticated: in high school, she was an Intel finalist with a mathematical model explaining how asymmetry develops in the body. She has interned twice at the New York City Office of the Chief Medical Examiner: the first time working in their forensics laboratory, then with a pathologist, assisting with autopsies. She has recently graduated from Brown University, and will return this Fall as a Medical student. At ADARC, she worked with post-doctoral fellow Faye Yu. They studied monoclonal antibody Ibalizumab, with the goal of enhancing its ability to firmly bind CD4 cells.   

      

Alice
Alice Raymond

Alice Raymond, an intern in Dr. Theodora Hatziioannou's laboratory, made an important decision at age twelve: she would find a vaccine against HIV. Inspired by her native France's annual Telethon, she committed to someday ending the epidemic. As she grew up and learned the complicated science behind the challenge, she understood it wouldn't be quite so simple. That decision guided her career in HIV/AIDS research.  

 

Here at ADARC, she is working on a restriction factor named Apobec. Apobec  

is present in our own cells and can inhibit HIV-1 infection, but HIV expresses another protein, Vif, which can counteract Apobec. She and her colleagues are testing several Vif proteins against Apobec to study this interaction.

 

 

 

Academic Seminars   
Seminars geared toward the scientific community and held at ADARC at 12pm. To attend, please email mbell@adarc.org.              

Friday, October 7

Lynn Morris, PhDNational Institute for Communicable Diseases / Africa


"HIV neutralizing antibodies - have we got enough now?"  

In This Issue
New Grant
Meet Our Interns
ADARC Seminar Series
Join Us 


Private support is vital to ADARC's mission - it allows rapid exploration of  new ideas before they can attract government funding. We count on your support to sustain an agile and creative research environment.

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